Facial volume loss can happen slowly. The cheeks may look flatter, the under-eye area may appear more hollow, or deeper lines may become harder to ignore. Some patients want to address these changes without synthetic filler materials. At MyHealth1st, our Volume Plus Protocol combines PRF facial injections with Bio Filler to restore soft volume while supporting healthier-looking skin.
Key Takeaways
• Bio Filler provides natural-looking volume in areas that have started to look hollow or less defined.
• PRF facial injections use concentrated growth factors to support collagen, elasticity, and skin renewal.
• Combining the two allows us to address facial shape and skin quality during the same treatment plan.
How Is Bio Filler Made?
Bio Filler begins with a small blood draw. We process the blood to isolate Platelet-Rich Fibrin, then use a heating and cooling process to create a smooth albumin gel. That gel is blended with liquid PRF to produce an injectable treatment made without synthetic filler materials.
Bio Filler can be placed in areas that need gentle lift or fullness, including the cheeks, lips, smile lines, temples, and jawline. It provides immediate soft volume with a subtle finish. As the material is gradually reabsorbed, it continues supporting collagen and elastin production.
What Do PRF Facial Injections Add?
Bio Filler helps restore structure, while PRF facial injections focus more directly on regeneration. Liquid PRF contains platelets, fibrin, and growth factors collected from your own blood. When injected into targeted areas, it supports natural tissue repair and collagen formation.
Research into injectable PRF for facial rejuvenation is still developing, but a systematic review of injectable PRF treatments found improvements in skin texture, elasticity, wrinkles, and patient satisfaction across several studies. PRF is not meant to create a dramatic overnight transformation. Its appeal comes from gradual changes as the skin responds.
How Does the Volume Plus Protocol Combine Them?
Our Volume Plus Protocol brings these treatments together. Bio Filler is used where the face needs more fullness or contour, while additional liquid PRF is injected beneath the skin to address wrinkles, skin quality, and volume loss.
This combination may be useful for deeper wrinkles, facial hollowing, reduced contour, and skin that looks thin, dry, or damaged. Instead of treating every concern with the same injectable, we can use each part of the protocol for a different purpose.
During your consultation, we will review your medical history, facial structure, and goals before determining whether Volume Plus is appropriate for you.
What Kind of Results Can You Expect?
Some soft volume may be visible soon after treatment, while improvements related to collagen and skin quality appear more gradually. The goal is a refreshed result that still looks like you, not an exaggerated or overfilled appearance.
Temporary swelling, redness, tenderness, or bruising may occur around the injection sites. The amount of treatment needed depends on the areas being addressed and the level of volume restoration you want.
Restore Volume Without Losing Your Natural Look
The Volume Plus protocol is a method of regeneration that can help to decrease the appearance of hollowness in facial areas, increase definition and/or reduce sagging in facial areas, and create an environment for healthy skin through PRF made from your own blood. Schedule a consultation at MyHealth1st to determine if you would benefit from injecting bio fillers into your face along with a PRF injection.


