ModeraFlam® offers targeted IL-6 inflammation support using nesem® citrus extracts and ASU to help modulate acute and chronic inflammation, joint pain, and systemic inflammatory states.
$67.50
ModeraFlam® is a practitioner-grade anti-inflammatory formula combining specific citrus-derived nesem® molecules, quercetin, and Avocado–Soybean Unsaponifiables (ASU). These compounds are scientifically recognized for their ability to interact directly with the Interleukin-6 (IL-6) inflammatory pathway, a central regulator of inflammation.
ModeraFlam® diminishes or blocks a wide range of inflammatory mediators including IL-6, NF-κB, JNK, and MAPK, and deactivates pro-inflammatory pathways downstream of IL-6 such as STAT3 .
The bioactive nesem® compounds provide benefits beyond antioxidant action, using a non-antioxidant pathway to influence inflammation and oxidative stress .
ASU, a specialized extract of avocado and soybean oils, is validated to reduce production of pro-inflammatory mediators and support joint mobility and cartilage integrity .
ModeraFlam® is formulated to help address all three stages of inflammatory activity:
Acute inflammation — helps regulate excessive or uncontrolled inflammatory responses.
Hyper-inflammation — modulates cytokine-driven pathways that can escalate into severe symptoms.
Chronic inflammation — supports long-term inflammatory balance linked to metabolic, autoimmune, and degenerative conditions
